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Image Search Results
Journal: Microscopy research and technique
Article Title: Stromal cells of giant cell tumor of bone show primary cilia in giant cell tumor of bone.
doi: 10.1002/jemt.23976
Figure Lengend Snippet: Fig. 1. Histological diagnosis and preliminary study of GCTB. a) Hematoxylin-Eosin staining shows two cellular types in GCTB: mononuclear and multinuclear giant cells (GC). Some of the mononuclear cells showed a characteristic paranuclear vacuole (arrow). Scale bar = 50μm b) CD68 is a specific marker for monocyte-macrophage lineage. Thus, histiocytic mononuclear cells and giant cells (GC) expressed CD68. Scale bar = 50μm c) Histone H3.3 G34W mutation is a specific marker of the stromal neoplastic cells of GCTB. According to this, only mononuclear cells were stained, some of them expressing paranuclear vacuoles (arrow).Scale bar = 50μm d) Immunolabeling for Ki67, marker of cell cycle activation and proliferation, stained uniquely mononuclear cells. Scale bar = 100μm
Article Snippet: Primary antibodies used in this study were:
Techniques: Biomarker Discovery, Staining, Marker, Mutagenesis, Expressing, Immunolabeling, Activation Assay
Journal: Microscopy research and technique
Article Title: Stromal cells of giant cell tumor of bone show primary cilia in giant cell tumor of bone.
doi: 10.1002/jemt.23976
Figure Lengend Snippet: Fig.5. Stromal cells show primary cilia. a) Immunofluorescent co-localisation of Histone H3.3 G34W mutation in green and Arl13b (ciliary membrane) in red showed that some stromal cells present primary cilia. Scale bar = 20μm b-d) Magnification of cells showing Histone H3.3 G34W mutation and Arl13b co-localisation.
Article Snippet: Primary antibodies used in this study were:
Techniques: Mutagenesis, Membrane